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Human ROR2 / NTRKR2 Protein, His Tag

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RO2-H52E5-50ug
¥3865.00
RO2-H52E5-1mg (500ug X 2)
¥26460.00
合计0件 产品金额¥ 0

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  • 分子别名(Synonym)

    ROR2,NTRKR2

  • 表达区间及表达系统(Source)

    Human ROR2, His Tag (RO2-H52E5) is expressed from human 293 cells (HEK293). It contains AA Glu 34 - Gly 403 (Accession # NP_004551.1).

    Predicted N-terminus: Glu 34

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    ROR2 Structure

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 43.2 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    95% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    ROR2 SDS-PAGE

    Human ROR2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • 活性(Bioactivity)-ELISA

     ROR2 ELISA

    Immobilized Human ROR2, His Tag (Cat. No. RO2-H52E5) at 1 μg/mL (100 μL/well) can bind Anti-ROR2 Antibody, Human IgG1 with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol

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背景介绍

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

前沿进展

 
药物研发进展
  • 英文全称:

    Tyrosine-protein kinase transmembrane receptor ROR2

  • 中文全称:

    蛋白酪氨酸激酶跨膜受体ROR2

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    1 详情

  • 最高研发阶段:

    临床二期

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