IgG

IgG

IgG Overview

Molecule Name
Immunoglobulin G
Synonyms
IgG
Drug Development Progress
Drugs in Clinical Trials8
Approved Drugs1
Highest Development StageApproved
Target Synonym
Immunoglobulin G
Background
The Anti-Human IgG-Acridine Ester is an acridinium ester labeled Monoclonal mouse anti-human IgG antibody can be used to capture the human IgG in Chemiluminescence procedures. The antibody reacts with the Fc portion of human IgG heavy chain but not with the Fab portion of human IgG. No antibody was detected against human IgM or IgA, or against non-immunoglobulin serum proteins. The antibody has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with mouse, cynomolgus and bovine serum proteins, but it is not sure if the product cross-react with immunoglobulins from other species. Acridinium ester is one of the most commonly used excited substrates for protein labeling and widely used in automated instruments because of its high sensitivity with detection limits in the attomole range. Acridinium ester can be triggering by chemiluminescent substrate solution and generate intense signal, the result signals (relative light units, RLU) can be measured at 430 nm. The Anti-human IgG-Acridine Ester is easy to capture the human IgG, and the bounded human IgG have no activity lost, this ready to use products could greatly save your protein labeling time and hassle, and help us get the best performance and highly reproducible results.

IgG Product List

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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
RicefidaseKJ-103; KJ103Phase 3 ClinicalShanghai Bao Pharmaceuticals Co Ltd
Anti-Glomerular Basement Membrane Disease; Guillain-Barre Syndrome; Rejection of renal transplantation
Details
AT-02AT-02Phase 2 ClinicalAttralus Inc
Amyloidosis; Immunoglobulin Light-chain Amyloidosis
Details
JZB-34AAFP; JZB-34Phase 1 ClinicalShanghai Kexin Biotech Co Ltd
Hypersensitivity
Details
Emicizumab biosimilar (Jushi Biopharmaceutical)SYS6053; SYS-6053Phase 1 ClinicalJushi Biopharmaceutical Co Ltd
Hemophilia A; Hemorrhage
Details
S-1117S-1117Phase 1 ClinicalSeismic Therapeutics Inc
Immune System Diseases
Details
BHV-1300BHV-1300Phase 1 ClinicalBiohaven Pharmaceuticals Inc
Arthritis, Rheumatoid; Graves Disease
Details
HNSA-5487HNSA 5487; HNSA-5487Phase 1 ClinicalHansa Biopharma Ab
Autoimmune Diseases; Neoplasms
Details
Anti-CD33/anti-FcgammaRI bispecific antibody (UCSD)Phase 1 ClinicalUniversity Of California San Diego
Leukemia, Myeloid, Acute
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyFirst Brand NameFirst Approved CountryFirst IndicationFirst Approved CompanyFirst Approved DateIndicationClinical Trial
ImlifidaseMac-1ApprovedHansamed IncIdefirixEURejection of renal transplantationHansa Biopharma Ab2020-08-25
Guillain-Barre Syndrome; Kidney Diseases; Kidney Failure, Chronic; Purpura, Thrombotic Thrombocytopenic; Rejection of renal transplantation; Rejection of organ transplantation; Renal Insufficiency, Chronic
Details