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Influenza A virus (A/Croatia/10136RV/2023) & (A/District of Columbia/27/2023) NA(H3N2) Protein, His Tag

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NEE-V524x-100ug
¥3675.00
NEE-V524x-1mg
¥28140.00
合计0件 产品金额¥ 0

产品详情

  • 分子别名(Synonym)

    NA,Neuraminidase

  • 表达区间及表达系统(Source)

    Influenza A virus (Croatia/10136RV) & (Columbia/27) NA(H3N2) Protein, His Tag (NEE-V524x) is expressed from human 293 cells (HEK293). It contains AA Ile 30 - Thr 469 (Accession # EPI3472932 & EPI2990330, GISAID).

    Predicted N-terminus: His

    Request for sequence

  • 蛋白结构(Molecular Characterization)

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 51.0 kDa. The protein migrates as 60-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 500 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 运输(Shipping)

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • 存储(Storage)

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 电泳(SDS-PAGE)

    Neuraminidase (NA) SDS-PAGE

    Influenza A virus (Croatia/10136RV) & (Columbia/27) NA(H3N2) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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背景介绍

Influenza, commonly known as 'the flu', is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle which makes it a great target for vaccine studies.

前沿进展

 
药物研发进展
  • 英文全称:

    Neuraminidase

  • 中文全称:

    神经氨酸苷酶

  • 种类:

  • 上市药物数量:

    4 详情

  • 临床药物数量:

    5 详情

  • 最高研发阶段:

    批准上市

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