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PE-CY7-Labeled Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3)

COAMS
DS

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货号-规格
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FABm002-04-50tests
¥2015.00
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产品详情

  • 抗体来源（Source）

    Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3) is a mouse monoclonal antibody produced from hybridoma.

  • 应用（Application）

    Flow Cytometry (Detection the expression of CD4 on Human cells).

  • 种属（Species）

    Mouse

  • 亚型（Isotype）

    Mouse IgG1 | Mouse kappa

  • 特异性（Specificity）

    This product is a specific antibody specifically reacts with CD4 protein.

  • 种属反应性（Reactivity）

    Human

  • 免疫原（Immunogen）

    Purified Human CD4 Protein.

  • 偶联（Conjugate）

    PE-CY7

    Excitation Wavelength: 561 nm

    Emission Wavelength: 780 nm

  • 推荐稀释比（Recommended Dilution）

    1:20

  • 制剂（Formulation）

    Supplied as 0.2 μm filtered solution in PBS, 0.2% BSA, 0.03% Proclin 300, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 存储（Storage）

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. Store at 2-8 °C for 12 months.

  • 质量管理控制体系（QMS）

    1. 质量管理体系（ISO, GMP）
    2. 质量优势
    3. 质控流程

产品展示

  • 活性（Bioactivity）-FACS

    CD4 FACS

    Flow cytometric analysis of Human peripheral blood lymphocytes respectively staining with PE-CY7-Labeled Anti-Human CD4 Antibody Mouse IgG1 (Cat. No. FABm002-04) at 1:20 dilution (5 μL of the antibody stock solution corresponds to labeling of 2.5e5 cells in a final volume of 100 µL), compared with isotype control antibody. PE-CY7 signal was used to evaluate the binding activity (QC tested).

    Protocol

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背景介绍

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

前沿进展

 
药物研发进展
  • 英文全称：

    T-cell surface antigen CD4

  • 中文全称：

    T细胞表面抗原CD4

  • 种类：

  • 上市药物数量：

    1 详情

  • 临床药物数量：

    22 详情

  • 最高研发阶段：

    批准上市

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