Human NT-4 / Neurotrophin-4 Protein, Tag Free, low endotoxin (MALS verified)

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NT4-H5114-20ug
$260.00
In Stock - Delivery in 2-3 business days
NT4-H5114-50ug
$385.00
In Stock - Delivery in 2 weeks
NT4-H5114-500ug (250ug X 2)
$2,320.00
In Stock - Delivery in 2 weeks
NT4-H5114
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Synonyms

neurotrophic factor 4, neurotrophic factor 5, neurotrophin 4, neurotrophin 5, neurotrophin-5, NT4, NT-4, 5, NT-5, NTF4, NTF5, GLC10

Source

Human NT-4, Tag Free (NT4-H5114) is expressed from E. coli cells. It contains AA Gly 81 - Ala 210 (Accession # P34130-1).

Predicted N-terminus: Met

Molecular Characterization

This protein carries no "tag".

The protein has a calculated MW of 14.1 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

バックグランド

Neurotrophin-4 (NT-4), also known as NT-5, is a member of the NGF family of neuronal and epithelial growth factors. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT-3, and NT-4/5. These secreted cytokines are synthesized as prepropeptides that are proteolytically processed to generate the mature proteins. Their functions including supporting the survival and differentiation of existing neurons, encouraging the growth and differentiation of new neurons and synapses, are required in both the central and the peripheral nervous systems.