Human MMP-10 Protein, Tag Free (active enzyme)

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MM0-H5214-100ug
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MM0-H5214-1mg
$2,730.00
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Synonyms

SL-2, STMY2

Source

Human MMP-10 Protein, Tag Free (MM0-H5214) is expressed from human 293 cells (HEK293). It contains AA Tyr 18 - Cys 476 (Accession # P09238).

Predicted N-terminus: Tyr 18

Molecular Characterization

This protein carries no "tag".

The protein has a calculated MW of 52.3 kDa. The protein migrates as 24-25 kDa, 43-46 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>85% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

Background

MMP‑12 (macrophage elastase) is a metalloendopeptidase predominantly produced by activated macrophages. It degrades elastin and other extracellular matrix components, shaping tissue remodeling and inflammatory responses. MMP‑12 is strongly implicated in chronic inflammation, COPD, and tumor microenvironment regulation, making it a relevant biomarker and therapeutic target.