GMP Human FGF basic Protein

FGF-2 (Fibroblast Growth Factor-2)​ is a central member of the FGF family, with potent mitogenic and angiogenic activities. In MSC culture, FGF-2 is a key factor for maintaining MSC proliferation capacity, delaying senescence, and preserving multipotency, effectively enhancing MSC expansion efficiency and therapeutic potential. In iPSC culture, FGF-2 is a fundamental cytokine for maintaining self-renewal and pluripotency, inhibiting spontaneous differentiation through pathways such as MAPK/ERK activation, and also serves as an important signaling molecule for differentiation into various lineages, including neural and mesodermal lineages.

• Specific Stem Cell Expansion Driver​: Efficiently supports hPSC and MSC expansion while maintaining stemness over multiple passages.
• Reliable Large-Scale Supply: Ensures batch production capacity, supporting robust and consistent manufacturing scale-up.
• High Lot-to-Lot Consistency​: Ensures reliable and reproducible performance in every batch, supporting scalable applications.

• Quality Assurance: Global QMS with comprehensive and stringent QC release criteria.
• End-to-End GMP Compliance: Full manufacturing and QC under a cGMP system.
• Comprehensive Control of Adventitious Agents: Stringent biosafety from cell banks to final release.
• Comprehensive Regulatory Support: Includes RSF and DMF to meet global requirements.
• Resilient Supply Chain: Intelligent modular facilities ensure a stable global supply.
• Professional Support: Extensive manufacturing and application expertise to accelerate development.

chain1: Ala-Leu-Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His
chain2: Pro-Glu-Asp-Gly-Gly-Ser-Gly-Ala-Phe-Pro-Pro-Gly-His-Phe-Lys
(Routinely tested)

Less than 10 EU/mg, tested by the LAL method in compliance with USP <85> and Ph. Eur. 2.6.14.

<0.5 ng/µg of protein tested by ELISA.

<0.02 ng/μg of protein tested by qPCR.

Sterility testing was performed using the membrane filtration method in compliance with USP <71> and Ph. Eur. 2.6.1.

Negative

>95% as determined by SDS-PAGE.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with protectants.

Contact us for customized product form or formulation.

2R (13 mm neck finish)

This product is supplied and shipped on blue ice.

Upon receipt, store it immediately at -20°C or lower for long term storage.

Please avoid repeated freeze-thaw cycles.

• -20°C to -70°C for 5 years in lyophilized state;
• -70°C for 12 months under sterile conditions after reconstitution.