Human DLL3 (353-465) Protein, Mouse IgG2a Fc Tag, low endotoxin

Related Products: Cell line CHEK-ATP090, Bridging ELISA Kit BIS-A005
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DL3-H5259-100ug
$400.00
DL3-H5259-1mg
$2,600.00
DL3-H5259
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Synonyms

Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3

Source

Human DLL3 (353-465), Mouse IgG2a Fc Tag (DL3-H5259) is expressed from human 293 cells (HEK293). It contains AA Arg 353 - Glu 465 (Accession # Q9NYJ7-1).

Predicted N-terminus: Arg 353

Molecular Characterization

This protein carries a mouse IgG2a Fc tag at the C-terminus.

The protein has a calculated MW of 38.6 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

バックグランド

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.