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HEK293/Human SEZ6 Stable Cell Line

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CHEK-ATP183-2Vials (1Vial X 2)
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产品详情

    1. Genetically modified cell lines best reflect MOA (Mechanism of Action)
    2. Higher activity and larger assay window for robust and reproducible cell-based bioassay
    3. Comprehensive application data to support assay development and validation
    4. Full tracible record, stringent quality control and validated cell passage stability
    5. Parental cell line legally obtained from internationally recognized cell resource bank and commercially licensed
    6. Global commercial license assistance whenever regulatory filing is required
  • 描述(Description)

    The HEK293/Human SEZ6 Stable Cell Line was engineered to express the receptor full human SEZ6 (Uniprot: Q53EL9-1), used to mimic cancer target cells. Surface expression of human SEZ6 was confirmed by flow cytometry.

  • 应用说明(Application)

    • Useful for cell-based SEZ6 binding assay

  • 生长特性(Growth Properties)

    Adherent

  • 筛选标记(Selection Marker)

    Puromycin (2 μg/mL)

  • 培养基(Complete Growth Medium)

    DMEM + 10% FBS

  • 冻存液(Freeze Medium)

    Serum-free cell cryopreservation medium

  • 装量(Quantity)

    1 vial contains at least 5×10^6 cells in 1 mL serum-free cryopreservation medium

  • 存储(Storage)

    Frozen in liquid nitrogen.

  • 支原体检测(Mycoplasma Testing)

    Negative

  • 无菌检测(Sterility Testing)

    Negative

  • 使用说明(Instructions for Use)

    See data sheet for detailed culturing and assay protocol.

产品展示

  • Receptor Assay

     SEZ6 FACS

    Expression analysis of human SEZ6 on HEK293/Human SEZ6 Stable Cell Line by FACS.
    Cell surface staining was performed on HEK293/Human SEZ6 Stable Cell Line or negative control cell using anti-human SEZ6 antibody followed by staining with PE anti-human IgG Fc Antibody.

    Protocol
  • Passage Stability

     SEZ6 PASSAGE

    Passage stability analysis of receptors expression by FACS.
    Flow cytometry surface staining of human SEZ6 on HEK293/Human SEZ6 Stable Cell Line demonstrates consistent mean fluorescent intensity across passage 6-20.

    Protocol
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背景介绍

May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.

前沿进展

 
药物研发进展
  • 英文全称:

    Seizure protein 6 homolog

  • 中文全称:

    癫痫发作蛋白6

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    2 详情

  • 最高研发阶段:

    临床一期

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