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ActiveMax® Human MSLN μBeads, premium grade (for cells)DMF

  • GMP version undefined is now available for seamless transition.
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  • Product
    Size
    Amount
    ActiveMax® Human MSLN μBeads, premium grade (for cells)
    2.5 mg
    2.5 × 10⁷ beads
    ActiveMax® Human MSLN μBeads, premium grade (for cells)
    10 mg (2.5 mg × 4)
    1.0 × 10⁸ beads
  • 背景(Background)

    ActiveMax® Human MSLN μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

  • 表达区间及表达系统(Source)

    ActiveMax® Human MSLN μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface and coupled with biotinylated Human MSLN Protein, expressed from human 293 cells (HEK293) and contains AA Glu 296 - Gly 580 (Accession # AAH09272.1).

  • 应用说明(Application)

    ActiveMax® Human MSLN μBeads, premium grade (for cells) are designed to stimulate in vitro MSLN-specific CAR-T cells or UCAR-T cells, similar to the tumor cell lines that express human MSLN antigen. It can be used as follows:
    Evaluating the characteristics of CAR-T cells or UCAR-T cells.
    In vitro expansion of MSLN-specific CAR-T cells or UCAR-T cells.
    In vitro enrichment of MSLN-specific CAR-T cells or UCAR-T cells.

    * We also carry ActiveMax® Streptavidin μBeads, premium grade (for cells)(Cat. No. MBS-C009), and it can be used for convenient preparation of your own sterile protein/antibody coupled beads for cell-based assay, cell sorting, and other applications. The ActiveMax® Streptavidin μBeads, premium grade can also be used together with other ActiveMax® μBeads, premium grade as Isotype control.

  • 重构方法(Reconstitution)

    See Certificate of Analysis (CoA) for detailed instruction.

  • 存储(Storage)

    This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

    Please avoid repeated freeze-thaw cycles after reconstitution. Immediate use after reconstitution is highly recommended.

  • 无菌(Sterility)

    Negative

  • 内毒素(Endotoxin)

    Less than 0.002 EU per μg by the LAL method.

  • 注意事项(Important Note)

    This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

  • 制剂(Formulation)

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

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  • 典型数据-Typical Data

    Please refer to DS document for the assay protocol.

     Mesothelin TYPICAL DATA

    Assay of human MSLN protein on the μBeads surface by Flow cytomtry. ActiveMax® Human MSLN μBeads, premium grade (for cells) (Cat. No. MBS-C003) were stained with anti-human MSLN antibody, and then followed by FITC anti-human IgG Fc antibody and analyzed by flow cytometry.

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前沿进展

 
药物研发进展
  • 英文全称:

    Mesothelin

  • 中文全称:

    间皮素

  • 种类:

  • 上市药物数量:

    0 详情

  • 临床药物数量:

    41 详情

  • 最高研发阶段:

    临床二期

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