ActiveMax® Human DLL4 μBeads, premium grade (for cells)

ActiveMax® Human DLL4 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm in diameter immobilized with Human DLL4 Protein, expressed from human 293 cells (HEK293) and contains AA Ser 27 - Pro 524 (Accession # NP_061947.1 ).
ActiveMax® Human DLL4 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

ActiveMax® Human DLL4 μBeads, premium grade (for cells) can activate Notch signaling in hematopoietic stem/progenitor cells (HSPCs), mimicking DLL4+ epithelial cells in the thymus, and then drives T-lineage commitment and differentiation. It can be used for in vitro production of induced pluripotent stem cell derived T cells, such as inducing the differentiation from CD34+ cells to progenitor T cells to TCRαβ T cells in vitro, which provides a simple and robust tool to both study human T cell development and facilitate the development of engineered T cell therapies from renewable sources.

See Certificate of Analysis (CoA) for detailed instruction.

This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.

Please protect from light and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended.

Negative

Less than 0.002 EU per μg by the LAL method / rFC method.

Negative

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

Lyophilized in PBS with 0.1% HSA，pH 7.4. Trehalose is added as protectant before lyophilization.