Cellectra™ Anti-G4S linker NanoSort Microbeads, Research grade

Anti-G4S Linker NanoSort MicroBeads, Research Grade are dextran-coated superparamagnetic iron oxide nanoparticles conjugated with recombinant monoclonal antibodies specific for the G4S linker (isotype: rabbit IgG). They are designed for the positive selection and enrichment of G4S-containing CAR-expressing cells.
Anti-G4S Linker NanoSort MicroBeads, Research Grade are produced under sterile manufacturing conditions (ISO 5), and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.

Cellectra™ Anti-G4S Linker NanoSort MicroBeads, Research Grade are designed for the positive selection and enrichment of CAR-modified cells expressing a G4S linker during CAR-T cell manufacturing following gene transduction. Anti-G4S Linker specifically recognizes the G4S (GGGGS) linker, a flexible peptide widely used in CARs and other recombinant proteins. Unlike antigen-specific reagents, it targets the conserved G4S sequence, providing a universal, antigen-independent solution for the detection, enrichment, and isolation of G4S-containing engineered cells. Its compatibility with diverse CAR constructs simplifies reagent development, streamlines workflows, and ensures consistent performance in research and cell manufacturing applications. The MicroBeads are conjugated with monoclonal antibodies specific for the G4S linker, enabling selective labeling and rapid magnetic enrichment of G4S-containing CAR-expressing cells using magnetic separation columns.

For long term storage, the product should be stored at liquid state at -20°C or below. Stability upon receipt: • Stable for 24 months at -20 °C or below; • Stable for 8 months at 2–8 °C under sterile conditions.

Please protect from light and avoid repeated freeze-thaw cycles.

Negative

Less than 2 EU per mL by the LAL method / rFC method.

Negative

This product is for research use only and not intended for therapeutic or in vivo diagnostic use.

Supplied in PBS buffer containing EDTA, rHSA and Poloxamer 188.