Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3)

Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3) is a PD-1 primary antibody for IHC application. Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.

LEICA Experiment Protocol

Shipped at 4°C, Blue Ice. Store at +4°C for 14 days. Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.