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Polyclonal Olig2 Antibody, Rabbit IgG

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OL2-S456-20ul
$80.00
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OL2-S456-100ul
$415.00
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OL2-S456
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製品詳細
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  • 製品詳細
  • データ表示
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Polyclonal Olig2 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
Gene Synonyms: Oligo2, bHLHe19, oligodendrocyte transcription factor 2.

Antibody Type

Polyclonal Antibody

Clone

AS456

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit polyclonal antibodies

Reactivity

Rabbit

Immunogen

Mouse Olig2 peptide fused to GST

Specificity

Usually, it is easier to get a positive signal in sections of juvenile animals than that of adults. This antibody does not recognize Olig1 and Olig3.

Application
Application
Recommended Use / Performance
IF
1:200
Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS containing 50 mM Glycine and 50 mM Tris, with 40% glycerol as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Shipped at -20°C. Store at -70°C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

バックグランド

The oligodendrocyte transcription factor 2 (Olig2) is a basic helix-loop-helix transcription factor which is highly expressed in the oligodendrocyte-lineage cells and in oligodendroglial tumors of the brain as well. Olig2 is an essential regulator of ventral neuroectodermal progenitor cell fate, especially regulating key stages of early oligodendrocyte development. Olig2 has also been reported to act as a gene repressor to determine the cell fate of motor neurons in the spinal cord. Olig2 is a useful marker for primary and mature oligodendrocytes as well as a marker of malignant glioma.

Zhang K, et al. Nat Commun. 2022;13(1):1423. doi: 10.1038/s41467-022-29068-z.

Ono K, et al. Mol Cells. 2009;27(4):397-401. doi: 10.1007/s10059-009-0067-2.

General Notes: FOR RESEARCH USE ONLY.