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Recombinant Monoclonal Anti-Ki-67 Antibody, Rabbit (7A4) is a Ki-67 primary antibody for IHC application. Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly . Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility.
Host Species | Rabbit |
Isotype | Rabbit IgG, Rabbit Kappa |
Clone | 7A4 |
Application | IHC-P |
Dilution Ratio | 1: 200 - 1: 1000 |
Form | Liquid |
Clonality | Monoclonal |
Reactivity | Human |
Synonyms | PPP1R105, MIB-1, ki-67 |
Concentration | 0.9~1.1 mg/ml |
Specificity | React with Ki-67 protein on the intracellular area of target cells |
Purification Tech | Protein A |
Preservation | Tris buffer, 1% BSA |
Shipped at 4°C, Blue Ice. Store at +4°C for 14 days. Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.