Monoclonal Anti-Human Pertuzumab Antibody, Mouse IgG1 (4D9)

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HPB-Y2506-100ug
$315.00
In Stock - Delivery in 2-3 business days
HPB-Y2506-1mg
$2,079.00
In Stock - Delivery in 2-3 weeks
HPB-Y2506
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Source

Monoclonal Anti-Human Pertuzumab Antibody, Mouse IgG1 (4D9) (Cat. No. HPB-Y2506) is a mouse monoclonal antibody produced from a hybridoma generated by fusion of SP2/0 myeloma cells with mouse B lymphocytes.

Antibody Type

Hybridoma Monoclonal

Clone

4D9

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Specificity

Specifically recognizes Human Pertuzumab; This antibody is a neutralizing antibody.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Storage

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 12 months under sterile conditions.
Notices

Product Specific Notices: For research use only.

バックグランド

Pertuzumab (brand name Perjeta), a recombinant humanized monoclonal antibody developed by Roche/Genentech, targets HER2’s extracellular dimerization domain. It is indicated for HER2-positive breast cancer (early neoadjuvant/adjuvant, metastatic) in combination with trastuzumab and chemotherapy. Its mechanism blocks HER2 heterodimerization, inhibiting downstream signaling and inducing apoptosis.