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Recombinant Monoclonal Anti-GUCY2C Antibody, Rabbit (P1H7) is a GUCY2C primary antibody for IHC application.
GUCY2C binds the endogenous peptides guanylin and uroguanylin as well as the heat-stable E. coli enterotoxin. It converts those extracellular signals into cyclic GMP production and links ligand recognition to intracellular signaling at the plasma membrane and endoplasmic reticulum membrane. GUCY2C protein is expressed prominently in the gastrointestinal tract, with additional expression in the proximal digestive tract and renal system.
Host Species | Rabbit |
Isotype | Rabbit IgG, Rabbit Kappa |
Clone | P1H7 |
Application | IHC-P |
Dilution Ratio | 1: 100 - 1: 500 |
Form | Liquid |
Clonality | Monoclonal |
Reactivity | Human |
Synonyms | GC-C |
Concentration | 0.9~1.1 mg/ml |
Specificity | React with GUCY2C protein on the membrane of target cell/tissue |
Purification Tech | Fc-Tag |
Preservation | PBS, 11% Trehalose, 40% Glycerol, 0.03% Proclin 300, 0.05% BSA (pH7.3) |
Shipped at 4°C, Blue Ice. Store at +4°C for 14 days. Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.