Rabbit Anti-Mouse FMC63 Polyclonal Antibody (recommended for ADA assay)

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FM3-S93-100ug
$380.00
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FM3-S93-1mg (100ug X 10)
$2,715.00
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FM3-S93
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Source

Rabbit Anti-Mouse FMC63 Polyclonal Antibody is a polyclonal antibody purified from rabbit serum.

Antibody Type

Polyclonal Antibody

Clone

AS93

Host Species

Rabbit

Reactivity

Mouse

Immunogen

FMC63 scFv

Specificity

Recognizes FMC63 scFv specifically.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.