Monoclonal Anti-Human Enfortumab Antibody, Mouse IgG1 (7D6)

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ENB-MY2483-100ug
$355.00
In Stock - Delivery in 2-3 business days
ENB-MY2483-1mg (500ug X 2)
$2,695.00
In Stock - Delivery in 2 weeks
ENB-MY2483
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Source

Chimeric Monoclonal Anti-Human Enfortumab Antibody, Mouse IgG1 (7D6) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG1 constant domains.

Antibody Type

Recombinant Monoclonal

Clone

7D6

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Immunogen

Recombinant Human Enfortumab is expressed from human 293 cells

Specificity

Specifically recognizes Human Enfortumab; This antibody is a neutralizing antibody.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

バックグランド

Enfortumab, is a monoclonal antibody used to treat urothelial carcinoma. Specifically it is used for urothelial carcinoma that is Nectin-4 receptor positive. Enfortumab works by binding to the Nectin-4 receptor and inducing tumor cell apoptosis. Enfortumab is a recombinant IgG1 kappa, fully human monoclonal antibody that selectively binds with high affinity in a cell-based assay to the extracellular domain of the human Nectin-4 protein.