Monoclonal Anti-DXD Antibody, Mouse IgG1 (AM684)

Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
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DXD-M684-100ug
$360.00
In Stock - Delivery in 2-3 business days
DXD-M684-1mg (100ug X 10)
$2,270.00
In Stock - Delivery in 2-3 business days
DXD-M684
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Source

Chimeric Monoclonal Anti-DXD Antibody, Mouse IgG1 (AM684) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG1 constant domains.

Antibody Type

Recombinant Monoclonal

Clone

AM684

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Immunogen

DXD-BSA

Specificity

Specifically recognizes the target-DXD.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

バックグランド

DXD (Exatecan derivative) is a potent DNA topoisomerase I inhibitor and is widely used as a cytotoxic payload of antibody-drug conjugates (ADCs) for the treatment of multiple cancers. Anti-DXD antibody is a mouse monoclonal antibody. This antibody has been validated for use in PK, PD, immunoassays, and ELISA.