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Recombinant Monoclonal Anti-CD5 Antibody, Rabbit (4G5) is a CD5 primary antibody for IHC application. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
Host Species | Rabbit |
Isotype | Rabbit IgG, Rabbit Kappa |
Clone | 4G5 |
Application | IHC-P |
Dilution Ratio | 1: 500 - 1: 2000 |
Form | Liquid |
Clonality | Monoclonal |
Reactivity | Human |
Synonyms | Leu-1 |
Concentration | 0.9~1.1 mg/ml |
Specificity | React with CD5 protein on the membrane of target cell/tissue |
Purification Tech | Protein A |
Preservation | Tris buffer, 1% BSA |
Shipped at 4°C, Blue Ice. Store at +4°C for 14 days. Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.