Monoclonal Anti-Bevacizumab Antibody, Mouse IgG1 (AY12)

Monoclonal Anti-Bevacizumab Antibody, Mouse IgG1 (AY12) (Cat. No. BEB-Y12) is a mouse monoclonal antibody produced from a hybridoma generated by fusion of SP2/0 myeloma cells with mouse B lymphocytes.

Hybridoma Monoclonal

AY12

Mouse IgG1, Kappa

Mouse

AY12 is an inhibitory anti-idiotype monoclonal antibody that specifically recognizes Bevacizumab. No detectable binding to the tested human IgG1 controls, VEGF165, Trastuzumab, or Adalimumab was observed under the tested conditions. AY12 inhibits the binding of Bevacizumab to VEGF165.

Protein A purified.

Less than 5%, as determined by SEC-MALS.

Please refer to the Certificate of Analysis (CoA).

Lyophilized

Lyophilized from a 0.22 μm-filtered solution in Tris (pH 7.5) containing 100 mM Glycine, 25 mM Arginine, 150 mM NaCl and 0.01% Tween80, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Lyophilized product is shipped at ambient temperature.

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

• -20°C to -70°C for 12 months in lyophilized state;
• -70°C for 3 months under sterile conditions after reconstitution.

Product Specific Notices: For research use only.