Monoclonal Anti-Adalimumab Antibody, Mouse IgG1 (AY19)

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ADB-Y19-100ug
$355.00
In Stock - Delivery in 2-3 business days
ADB-Y19-1mg (500ug X 2)
$2,695.00
In Stock - Delivery in 2-3 business days
ADB-Y19
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Source

Monoclonal Anti-Adalimumab Antibody, Mouse IgG1 (AY19) (Cat. No. ADB-Y19) is a mouse monoclonal antibody produced from a hybridoma generated by fusion of SP2/0 myeloma cells with mouse B lymphocytes.

Antibody Type

Hybridoma Monoclonal

Clone

AY19

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Specificity

AY19 is an inhibitory anti-idiotype monoclonal antibody that specifically recognizes Adalimumab. No detectable binding to the tested human IgG1 controls, TNF-alpha, Trastuzumab, or Bevacizumab was observed under the tested conditions. AY19 inhibits the binding of Adalimumab to TNF-alpha.

Application
Application
Recommended Use / Performance
ELISA
2-20 ng/mL
Blocking Elisa
0.03-0.24 μg/mL
ADA Assay Development
Validated as a surrogate positive control in bridging ELISA assays.
(Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.)
Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in Tris (pH 7.5) containing 100 mM Glycine, 25 mM Arginine and 150 mM NaCl, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

バックグランド

Adalimumab is a human monoclonal antibody against TNF-alpha. It is produced by recombinant DNA technology using a mammalian cell expression system. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.