user
menu
letter
Sign InRegister
langEnglisharrow

TROP-2

TROP-2

TROP-2 詳細

Molecule Name
Tumor-associated calcium signal transducer 2
分子の別称
TACSTD2,GA733-1,M1S1,TROP2
Drug Development Progress
治験薬の数50
市販薬剤の数3
研究＆開発段階Approved
ターゲットの別称
Tumor-associated calcium signal transducer 2，M1S1，TROP2，TACSTD2，Pancreatic carcinoma marker protein GA733-1，Tumor Associated Calcium Signal Transducer 2，GA733-1，Membrane Component， Chromosome 1， Surface Marker 1，Gastrointestinal Tumor-Associated Antigen GA7331，Pancreatic Carcinoma Marker Protein GA7331，Cell surface glycoprotein Trop-2，Membrane component chromosome 1 surface marker 1，40kD Glycoprotein， Identified By Monoclonal Antibody GA733，Cell Surface Glycoprotein TROP2，Epithelial Glycoprotein-1，Truncated TACSTD2，GA7331，EGP-1，EGP1，GP50，Trophoblast Cell Surface Antigen 2
バックグランド
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

TROP-2 製品リスト

No Data
You Have Viewed 0 Of 0 Results
  • 1

Can’t find what you need?

Submit your requirements and our technical
team will help.

お問い合わせRequest Customization
  • M***g2023-07-06
    Human TROP-2 / TACSTD2 Protein, Fc Tag (MALS verified)
    This protein was used to immunize mice for antibody development. Proteins were mixed with CFA/IFA and immunized intraperitoneally. Mice were boosted every 14 days for 5 boosts following initial immunization. Serum titers were measured by ELISA following Days 0, 43, and 65. Of the two mice immunized with this protein, only one mouse developed an antibody response as low signal was detected at day 65.
  • V***w2023-02-21
    Human TROP-2 / TACSTD2 Protein, His Tag, low endotoxin (Mass Spec & MALS verified)
    Acro and their customer support are super helpful. Products ordered arrived in a timely manner. Customer support personal are as friendly as they are insightful. Never have they disappointed when purchasing any of their products. Such a user friendly website and if anything is not found customer support never backs down to help out! Acro’s personal are very friendly and knowledgeable. They were friendly and helpful when resolving this issue.
  • E***l2022-10-26
    Human TROP-2 / TACSTD2 Protein, His Tag, low endotoxin (Mass Spec & MALS verified)
    Acro’s customer support is always super helpful and quick to respond. When products are ordered, the arrive in a timely manner. Acro’s personal are very friendly and knowledgeable. They never disappoint when it comes to finding a solution to a problem. Having such a user-friendly website helps a lot in finding the right product needed and if something cannot be found customer support always finds a way!