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TOP2A

TOP2A信息

英文名称:Topoisomerase (DNA) II alpha上市药物数量1
中文名称拓扑异构酶2α临床药物数量1
靶点别称EC:5.6.2.2，EC 5.6.2.2，TOP2A，DNA topoisomerase 2-alpha，DNA topoisomerase II， alpha isozyme，DNA Topoisomerase II Alpha，Topoisomerase (DNA) II Alpha 170kDa，TOP2，DNA Topoisomerase (ATP-Hydrolyzing)，DNA Topoisomerase II， 170 KD，EC 5.99.1.3，TP2A，DNA Gyrase最高研发阶段Approved
英文名称:Topoisomerase (DNA) II alpha
中文名称拓扑异构酶2α
靶点别称EC:5.6.2.2，EC 5.6.2.2，TOP2A，DNA topoisomerase 2-alpha，DNA topoisomerase II， alpha isozyme，DNA Topoisomerase II Alpha，Topoisomerase (DNA) II Alpha 170kDa，TOP2，DNA Topoisomerase (ATP-Hydrolyzing)，DNA Topoisomerase II， 170 KD，EC 5.99.1.3，TP2A，DNA Gyrase
上市药物数量1
临床药物数量1
最高研发阶段Approved

TOP2A产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    Tag Free (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

TOP2A分子背景

DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.

TOP2A分子别名

TOP2A,TOP2,DNA topoisomerase 2-alpha,DNA topoisomerase II,alpha isozyme
  • 分子信息
  • 产品列表