TIM-1 詳細
Molecule Name
T-cell immunoglobulin mucin receptor 1
分子の別称
HAVCR1,KIM1,TIM1,TIMD1
Drug Development Progress
治験薬の数0
市販薬剤の数0
研究＆開発段階Discontinued
ターゲットの別称
CD365 Antigen，HAVCR，TIMD1，T-cell immunoglobulin mucin receptor 1，TIMD-1，TIM-1，CD365，TIM1，HAVCR1，Hepatitis A Virus Cellular Receptor 1，Kidney Injury Molecule 1，T-Cell Immunoglobulin Mucin Family Member 1，T-Cell Membrane Protein 1，KIM-1，KIM1，TIM，T Cell Immunoglobin Domain And Mucin Domain Protein 1，HAVcr-1，T-Cell Immunoglobulin And Mucin Domain-Containing Protein 1
バックグランド
Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.
TIM-1 製品リスト
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