SLC1A5

SLC1A5

SLC1A5 詳細

Molecule Name
Neutral amino acid transporter B(0)
分子の別称
ASCT2,M7V1,RDR,RDRC,ATB(0),AAAT,ASCT2M7VS1,M7V1ATBO,R16,RD114,RDRCFLJ31068
Drug Development Progress
治験薬の数0
市販薬剤の数0
研究&開発段階Preclinical
ターゲットの別称
ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5,ASCT2,M7V1,RDRC
バックグランド
Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).

SLC1A5 製品リスト

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