ROR2

ROR2

ROR2 詳細

Molecule Name
Tyrosine-protein kinase transmembrane receptor ROR2
分子の別称
ROR2,NTRKR2
Drug Development Progress
治験薬の数1
市販薬剤の数0
研究&開発段階Phase 2 Clinical
ターゲットの別称
EC:2.7.10.1,ROR2,NTRKR2,Receptor Tyrosine Kinase Like Orphan Receptor 2,Tyrosine-Protein Kinase Transmembrane Receptor ROR2,Neurotrophic Tyrosine Kinase, Receptor-Related 2,Neurotrophic Tyrosine Kinase Receptor-Related 2,Receptor Tyrosine Kinase-Like Orphan Receptor 2,EC 2.7.10.1,BDB1,BDB
バックグランド
Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

ROR2 製品リスト

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治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
Ozuriftamab VedotinHTBA-3021; CAB-ROR2; CAB-ROR2-ADC; CAB-ADC; BA-3021Phase 2 ClinicalBioatla
Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
詳細