ROBO1

ROBO1

ROBO1 Overview

Molecule Name
Roundabout homolog 1
Synonyms
ROBO1,DUTT1
Drug Development Progress
Drugs in Clinical Trials0
Approved Drugs0
Highest Development StagePending
Target Synonym
DUTT1,Roundabout homolog 1,ROBO1,Roundabout Guidance Receptor 1,Deleted In U Twenty Twenty,Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila),Roundabout (Axon Guidance Receptor, Drosophila) Homolog 1,Roundabout, Axon Guidance Receptor, Homolog 1,H-Robo-1,SAX3,FLJ21882
Background
ROBO1 is a member of the ROBO immunoglobulin superfamily of proteins, and it plays a crucial role in cell motility and migration during embryogenesis and organogenesis. In addition, evidence showed that ROBO1 might drive migration and invasion in malignant cells, such as glioma and breast cancer, which might play a role in cancer aggressiveness. In contrast, some studies suggested that ROBO1 pathways play a key role in tumors by acting as a tumor suppressor, especially in cell invasion.

ROBO1 Product List

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