IL-17 RB 詳細
Molecule Name
Interleukin-17 receptor B
分子の別称
IL-17 RB,Interleukin-17 receptor B,Interleukin-17 receptor B,Cytokine receptor-like 4,IL-17 receptor homolog 1,IL-17Rh1,IL17Rh1,Interleukin-17B receptor,IL-17B receptor,IL17RB,CRL4, EVI27, IL17BR
Drug Development Progress
治験薬の数1
市販薬剤の数0
研究＆開発段階Phase 2 Clinical
ターゲットの別称
IL-17 receptor B，IL-17RB，Cytokine receptor-like 4，IL-17 receptor homolog 1，IL-17Rh1，IL17Rh1，Interleukin-17B receptor，IL-17B receptor
バックグランド
IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.
IL-17 RB 製品リスト
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治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| SM-17 | SM-17; SM17 | Phase 2 Clinical | Sinomab Bioscience Ltd | Asthma; Dermatitis, Atopic; Idiopathic Pulmonary Fibrosis; Inflammatory Bowel Diseases | 詳細 |