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Her2

Her2信息

英文名称:Receptor protein-tyrosine kinase erbB-2上市药物数量40
中文名称受体蛋白酪氨酸激酶 erbB-2临床药物数量200
靶点别称EC 2.7.10.1，HER-2/Neu，Herstatin，HER-2，TKR1，Receptor， ErbB-2，V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2， Neuro/Glioblastoma Derived Oncogene Homolog，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2，Neuroblastoma/Glioblastoma Derived Oncogene Homolog，C-Erb B2/Neu Protein，CD340 Antigen，EC:2.7.10.1，EC 2.7.10，MLN 19，CD340，Tyrosine kinase-type cell surface receptor HER2，Receptor tyrosine-protein kinase erbB-2，ERBB2，MLN19，Proto-oncogene Neu，Erb-B2 Receptor Tyrosine Kinase 2，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2，Neuro/Glioblastoma Derived Oncogene Homolog，Human Epidermal Growth Factor Receptor 2，Metastatic Lymph Node Gene 19 Protein，Proto-Oncogene C-ErbB-2，P185erbB2，HER2，NGL，NEU，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog)最高研发阶段Approved
英文名称:Receptor protein-tyrosine kinase erbB-2
中文名称受体蛋白酪氨酸激酶 erbB-2
靶点别称EC 2.7.10.1，HER-2/Neu，Herstatin，HER-2，TKR1，Receptor， ErbB-2，V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2， Neuro/Glioblastoma Derived Oncogene Homolog，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2，Neuroblastoma/Glioblastoma Derived Oncogene Homolog，C-Erb B2/Neu Protein，CD340 Antigen，EC:2.7.10.1，EC 2.7.10，MLN 19，CD340，Tyrosine kinase-type cell surface receptor HER2，Receptor tyrosine-protein kinase erbB-2，ERBB2，MLN19，Proto-oncogene Neu，Erb-B2 Receptor Tyrosine Kinase 2，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2，Neuro/Glioblastoma Derived Oncogene Homolog，Human Epidermal Growth Factor Receptor 2，Metastatic Lymph Node Gene 19 Protein，Proto-Oncogene C-ErbB-2，P185erbB2，HER2，NGL，NEU，V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog)
上市药物数量40
临床药物数量200
最高研发阶段Approved

Her2产品列表

  • 属性

    Protein (29)Kits (2)Beads (1)Antibody (1)Cell Grade Beads (1)Cell (1)

  • 产品库

    在线 (37)

  • 物种

    Human (23)Mouse (5)Cynomolgus (4)Rabbit (3)

  • 标签

    His Tag (17)Fc Tag (4)Strep Tag (1)His Tag & Avi Tag (4)- (7)Tag Free (1)Mouse IgG Fc Tag (1)Fc Tag & Avi Tag (2)

  • 标记

    Biotin-labeled (7)Unconjugated (16) (3)FITC Labeled (2)PE Labeled (2)APC Labeled (2)AF647 Labeled (1)AF555 Labeled (1)AF488 Labeled (1)

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Her2分子背景

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

Her2分子别名

ERBB2,CD340,HER-2,neu,HER2,MLN19,NEU,NGL,TKR1

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