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EphA2

EphA2信息

英文名称:Ephrin type-A receptor 2上市药物数量2
中文名称A型肝配蛋白受体-2临床药物数量5
靶点别称EC:2.7.10.1，Epithelial Cell Receptor Protein Tyrosine Kinase，Ephrin type-A receptor 2，Epithelial cell kinase，EPHA2，EPH Receptor A2，Tyrosine-Protein Kinase Receptor ECK，ECK，Soluble EPHA2 Variant 1，EC 2.7.10.1，CTRCT6，ARCC2，CTPP1，CTPA，Receptor， EphA2，EC 2.7.10最高研发阶段Approved
英文名称:Ephrin type-A receptor 2
中文名称A型肝配蛋白受体-2
靶点别称EC:2.7.10.1，Epithelial Cell Receptor Protein Tyrosine Kinase，Ephrin type-A receptor 2，Epithelial cell kinase，EPHA2，EPH Receptor A2，Tyrosine-Protein Kinase Receptor ECK，ECK，Soluble EPHA2 Variant 1，EC 2.7.10.1，CTRCT6，ARCC2，CTPP1，CTPA，Receptor， EphA2，EC 2.7.10
上市药物数量2
临床药物数量5
最高研发阶段Approved

EphA2产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (2)Rat (1)

  • 标签

    His Tag (2)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (2)Biotin-labeled (1)

共 3 项数据
  • 1

EphA2分子背景

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.

EphA2分子别名

EphA2

产品评论

  • zh***chempartner.com 2024-03-19
    0人点赞
    Biotinylated Human EphA2 Protein, His,Avitag™ (MALS verified)
    我们购买该产品用于SPR亲和力测定，该产品质量较好，密封性好，包装一如既往的严实，最终实验结果也比较符合我们的期待值，自带纸质和二维码产品说明较为详细方便。
  • 分子信息
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