选择语言
免费注册
关注公众号

DM-1

DM-1信息

英文名称:Myotonin-protein kinase上市药物数量0
中文名称肌强直蛋白蛋白激酶临床药物数量3
靶点别称Myotonin-Protein Kinase，Dystrophia Myotonica 1，DMPK，MT-PK，DMK，Myotonic dystrophy protein kinase，DM1 protein kinase，DM1PK，Dystrophia Myotonica Protein Kinase，DM1，DM，DM Protein Kinase，Thymopoietin Homolog，MDPK，Myotonic Dystrophy Associated Protein Kinase，Dystrophia Myotonica 1 (Includes Dystrophia Myotonia Protein Kinase)，DM-kinase，Myotonin Protein Kinase A最高研发阶段临床三期
英文名称:Myotonin-protein kinase
中文名称肌强直蛋白蛋白激酶
靶点别称Myotonin-Protein Kinase，Dystrophia Myotonica 1，DMPK，MT-PK，DMK，Myotonic dystrophy protein kinase，DM1 protein kinase，DM1PK，Dystrophia Myotonica Protein Kinase，DM1，DM，DM Protein Kinase，Thymopoietin Homolog，MDPK，Myotonic Dystrophy Associated Protein Kinase，Dystrophia Myotonica 1 (Includes Dystrophia Myotonia Protein Kinase)，DM-kinase，Myotonin Protein Kinase A
上市药物数量0
临床药物数量3
最高研发阶段Phase 3 Clinical

DM-1产品列表

  • 属性

    Antibody (3)

  • 产品库

    在线 (3)

  • 物种

    Mouse (3)

  • 标签

    Mouse IgG1 (3)

  • 标记

    Unconjugated (1)HRP Labeled (1)Biotin-labeled (1)

共 3 项数据
  • 1

DM-1分子背景

Mertansine (DM-1) is a tubulin inhibitor that binds to the ends of microtubules and inhibits microtubule dynamics. DM-1(Mertansine) has antitumor activity and functions as a regulator of tubulin. It is an alpha-amino acid ester, a carbamate, an epoxide, an organic heterocyclic tetracyclic compound, an organochlorine compound, a mercaptan, and a maydenin alkaloid. DM-1, derived from Mydenin, is a cytotoxic component of antibody-drug conjugations that produce antibody-drug conjugations via a sulfhydryl group splice with SPP (n-succinimide 4- (2-pyridyl dithio)) or SMCC (4- (3-mercapto-2, 5-dioxy-1 pyrrolidyl) -cyclohexanic acid) splice.

DM-1分子别名

Mertansine， DM-1,DM1
  • 分子信息
  • 产品列表