DLK1 詳細
Molecule Name
Protein delta homolog 1
分子の別称
DLK1,FA1,Protein delta homolog 1,Pg2,Fetal antigen 1
Drug Development Progress
治験薬の数2
市販薬剤の数0
研究＆開発段階Phase 1 Clinical
ターゲットの別称
DLK1，DLK-1，DLK1 protein
バックグランド
Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene. It is expressed as a transmembrane protein, but a soluble form cleaved off by ADAM17 is active in inhibiting adipogenesis, the differentiation of pre-adipocytes into adipocytes.
DLK1 製品リスト
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治験薬に関する情報
| 英語名 | 研究コード | 研究開発ステージ | 会社 | 適応症 | 臨床試験 |
|---|---|---|---|---|---|
| CBA-1205 | CBA-1205 | Phase 1 Clinical | Chiome Bioscience Inc | Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Neuroblastoma; Solid tumours | 詳細 |
| ADCT-701 | ADCT-701; ADCT701; LIV-1205 ADC | Phase 1 Clinical | Adc Therapeutics Sa, Cancer Research Technology | Adrenocortical Carcinoma; Carcinoma, Neuroendocrine; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Small Cell Lung Carcinoma | 詳細 |