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CD79B

CD79B信息

英文名称:B-cell antigen receptor complex-associated protein beta chain上市药物数量1
中文名称B细胞抗原受体复合物相关蛋白β链临床药物数量9
靶点别称B-Cell Antigen Receptor Complex-Associated Protein Beta Chain,B29,Immunoglobulin-associated B29 protein,Ig-beta,B-cell-specific glycoprotein B29,CD79B,CD79b Molecule,CD79b Molecule, Immunoglobulin-Associated Beta,IGB,CD79B Antigen (Immunoglobulin-Associated Beta),CD79b Antigen,AGM6最高研发阶段批准上市
英文名称:B-cell antigen receptor complex-associated protein beta chain
中文名称B细胞抗原受体复合物相关蛋白β链
靶点别称B-Cell Antigen Receptor Complex-Associated Protein Beta Chain,B29,Immunoglobulin-associated B29 protein,Ig-beta,B-cell-specific glycoprotein B29,CD79B,CD79b Molecule,CD79b Molecule, Immunoglobulin-Associated Beta,IGB,CD79B Antigen (Immunoglobulin-Associated Beta),CD79b Antigen,AGM6
上市药物数量1
临床药物数量9
最高研发阶段Approved

CD79B产品列表

  • 属性

    Protein (9)Cell (1)

  • 产品库

    在线 (10)

  • 物种

    Human (5)Cynomolgus (2)Mouse (3)

  • 标签

    Fc Tag (2)His Tag (5)His Tag & Avi Tag (2)- (1)

  • 标记

    Unconjugated (6)Biotin-labeled (2)PE Labeled (1) (1)

共 10 项数据
  • 1

CD79B分子背景

B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

CD79B分子别名

CD79b,B29,IGB,Ig-beta

产品评论

  • 2025-03-13
    0人点赞
    已购买多次该公司的蛋白产品,效果均非常好,本次购买的为人源蛋白CDB-H5259的蛋白100ug,用于做验证试验,实验结果显著
  • zh*********lanovamed.com 2024-09-18
    0人点赞
    对比了几家,还是选择老朋友ACRO,一到货,就迫不及待的安排实验,实验结果达到预期,产品完全满足实验的要求,后续会继续采购。
  • 24********qq.com 2024-07-31
    0人点赞
    我们采购了CDB protein,设计了体外细胞实验,通过加入抑制剂,观察该蛋白与药物之间的相互作用关系,取得了良好且稳定的实验效果。实验重复性较高,价格合理,物流也很快,蛋白纯度较高,结果稳定。
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