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CD74

CD74信息

英文名称:HLA-DR antigens-associated invariant chain上市药物数量0
中文名称HLA-DR抗原相关不变链临床药物数量4
靶点别称CLIP，CD74，Ia antigen-associated invariant chain，CD74 Molecule，CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex， Class II Antigen-Associated)，CD74 Molecule， Major Histocompatibility Complex， Class II Invariant Chain，HLA-DR Antigens-Associated Invariant Chain，Ia-Associated Invariant Chain，MHC HLA-DR Gamma Chain，HLA-DR-Gamma，DHLAG，P33，CD74 Antigen，Ia-GAMMA，HLADG，II，Gamma Chain Of Class II Antigens，HLA Class II Histocompatibility Antigen Gamma Chain最高研发阶段Phase 2 Clinical
英文名称:HLA-DR antigens-associated invariant chain
中文名称HLA-DR抗原相关不变链
靶点别称CLIP，CD74，Ia antigen-associated invariant chain，CD74 Molecule，CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex， Class II Antigen-Associated)，CD74 Molecule， Major Histocompatibility Complex， Class II Invariant Chain，HLA-DR Antigens-Associated Invariant Chain，Ia-Associated Invariant Chain，MHC HLA-DR Gamma Chain，HLA-DR-Gamma，DHLAG，P33，CD74 Antigen，Ia-GAMMA，HLADG，II，Gamma Chain Of Class II Antigens，HLA Class II Histocompatibility Antigen Gamma Chain
上市药物数量0
临床药物数量4
最高研发阶段Phase 2 Clinical

CD74产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (3)

  • 标签

    His Tag (1)Fc Tag (1)Llama IgG Fc Tag (1)

  • 标记

    Unconjugated (3)

共 3 项数据
  • 1

CD74分子背景

Cluster of Differentiation 74 (CD74) is also known as HLA class II histocompatibility antigen gamma chain (HLADG), DHLAG, Ia-GAMMA, invariant chain (Abbreviated Ii). CD74 / HLADG is a polypeptide involved in the formation and transport of MHC class II protein. The cell surface form of the invariant chain is known as CD74. CD74 is upregulated in several cancers and is also expressed by non-immune cells during inflammation. CD74 plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha / beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal / lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. CD74 / DHLAG also serves as cell surface receptor for the cytokine MIF.

CD74分子别名

CD74,DHLAG,HLADG,II,Ia-GAMMA,p33,CLIP,INVG34

产品评论

  • 13*********126.com 2021-12-08
    3人点赞
    Human CD74 / DHLAG Protein, His Tag (HPLC verified)
    CD47带有his标签的靶点蛋白，经过和商业化抗体qc后，亲和力达到标准，用于小鼠免疫和杂交瘤的后期筛选，以拿到好亲和力的抗体进行后续人源化。
  • 分子信息
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