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CD30

CD30信息

英文名称:Tumor necrosis factor receptor superfamily member 8上市药物数量1
中文名称肿瘤坏死因子受体超家族成员8临床药物数量23
靶点别称CD30，CD30L receptor，TNFRSF8，Lymphocyte activation antigen CD30，TNF Receptor Superfamily Member 8，D1S166E，Tumor Necrosis Factor Receptor Superfamily， Member 8，Cytokine Receptor CD30，CD30 Antigen，Ki-1，Ki-1 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 8最高研发阶段Approved
英文名称:Tumor necrosis factor receptor superfamily member 8
中文名称肿瘤坏死因子受体超家族成员8
靶点别称CD30，CD30L receptor，TNFRSF8，Lymphocyte activation antigen CD30，TNF Receptor Superfamily Member 8，D1S166E，Tumor Necrosis Factor Receptor Superfamily， Member 8，Cytokine Receptor CD30，CD30 Antigen，Ki-1，Ki-1 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 8
上市药物数量1
临床药物数量23
最高研发阶段Approved

CD30产品列表

  • 属性

    Protein (8)Kits (1)

  • 产品库

    在线 (9)

  • 物种

    Human (9)

  • 标签

    Fc Tag (2)His Tag & Avi Tag (1)Llama IgG Fc Tag (1)His Tag (3)Fc Tag & Avi Tag (1)- (1)

  • 标记

    Unconjugated (3)Biotin-labeled (2)FITC Labeled (2)PE Labeled (1) (1)

共 9 项数据
  • 1

CD30分子背景

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

CD30分子别名

TNFRSF8,CD30,D1S166E,Ki-1

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