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CD30

CD30

CD30 詳細

Molecule Name
Tumor necrosis factor receptor superfamily member 8
分子の別称
TNFRSF8,CD30,D1S166E,Ki-1
Drug Development Progress
治験薬の数25
市販薬剤の数1
研究＆開発段階Approved
ターゲットの別称
CD30，CD30L receptor，TNFRSF8，Lymphocyte activation antigen CD30，TNF Receptor Superfamily Member 8，D1S166E，Tumor Necrosis Factor Receptor Superfamily， Member 8，Cytokine Receptor CD30，CD30 Antigen，Ki-1，Ki-1 Antigen，Tumor Necrosis Factor Receptor Superfamily Member 8
バックグランド
Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

CD30 製品リスト

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  • R*** 2021-09-22
    FITC-Labeled Human CD30 / TNFRSF8 Protein, His Tag
    Our research group work with CAR-T therapy for the treatment of hematological malignancies, and use the Fitc-Labeled Human CD30 protein for detection of CAR30 cells in patients by flow cytometry. Our results are fantastic, because the observe consistency and a reproducible experiments by flow cytometry. The logistic speed is very effective and allows us to work always up to date with our projects.
  • 1***22020-01-10
    Human CD30 / TNFRSF8 Protein, Fc Tag, low endotoxin (MALS verified)
    There are many CD30 products, with various tags. What I chose was the hFc tag protein. I also purchased CD30L for Fortebio experiment. The result was pretty good.