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CD117

CD117信息

英文名称:Stem cell growth factor receptor上市药物数量16
中文名称干细胞生长因子受体临床药物数量31
靶点别称EC 2.7.10，EC:2.7.10.1，MASTC，KIT Proto-Oncogene Receptor Tyrosine Kinase，V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein，p145 c-kit，SCFR，KIT，Proto-Oncogene C-Kit，Proto-Oncogene Tyrosine-Protein Kinase Kit，Soluble KIT Variant 1，C-Kit Protooncogene，CD117 Antigen，Piebald Trait，EC 2.7.10.1，C-Kit，CD117，Proto-Oncogene Proteins c-kit，Mast/stem cell growth factor receptor Kit，PBT，Piebald trait protein，Tyrosine-protein kinase Kit，KIT Proto-Oncogene， Receptor Tyrosine Kinase，v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog最高研发阶段NDA/BLA
英文名称:Stem cell growth factor receptor
中文名称干细胞生长因子受体
靶点别称EC 2.7.10，EC:2.7.10.1，MASTC，KIT Proto-Oncogene Receptor Tyrosine Kinase，V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein，p145 c-kit，SCFR，KIT，Proto-Oncogene C-Kit，Proto-Oncogene Tyrosine-Protein Kinase Kit，Soluble KIT Variant 1，C-Kit Protooncogene，CD117 Antigen，Piebald Trait，EC 2.7.10.1，C-Kit，CD117，Proto-Oncogene Proteins c-kit，Mast/stem cell growth factor receptor Kit，PBT，Piebald trait protein，Tyrosine-protein kinase Kit，KIT Proto-Oncogene， Receptor Tyrosine Kinase，v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
上市药物数量16
临床药物数量31
最高研发阶段NDA/BLA

CD117产品列表

  • 属性

    Protein (7)

  • 产品库

    在线 (7)

  • 物种

    Human (3)Rhesus macaque (1)Mouse (1)Cynomolgus (2)

  • 标签

    His Tag (2)Fc Tag (3)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (5)Biotin-labeled (2)

共 7 项数据
  • 1

CD117分子背景

Mast/stem cell growth factor receptor Kit (c-Kit), a member of the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily, is also known as piebald trait protein (PBT), p145 c-kit, tyrosine-protein kinase Kit and CD117,which contains five Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. CD117 acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, CD117 can activate several signaling pathways. Furthermore, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B.

CD117分子别名

CD117,SCFR,c-Kit,KIT

产品评论

  • zh*********lanovamed.com 2024-10-28
    0人点赞
    Biotinylated Human CD117 / c-kit Protein, His,Avitag (MALS verified)
    又来下单biotined产品了，主要用来做竞争的实验，已经噬菌体库的液相淘选。产品一如既往的稳定，实验结果符合预期，完美
  • 2022-07-13
    4人点赞
    Human CD117 / c-kit Protein, His Tag (MALS verified)
    We used the c-Kit protein to immunizations projects we are carrying for our studies and they performed great. The delivery was also very fast and the purchasing process very easy. We also purchased several other antibodies and recombinant proteins that we are currently testing and they all have very good quality. I have not used directly the technical services because it was not necessary, as the website is very easy and informative, so I found the products we wanted with no problem.
  • ya**********qq.com 2022-06-09
    1人点赞
    Cynomolgus CD117 / c-kit Protein, His Tag (MALS verified)
    无论在何地，无论在那个地点，我都要给acro好评。试剂活性好，分析无烦恼。正确认识和使用试剂的人，都会现在acro，网上还有方法。值得继续购买
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  • 分子信息
  • 产品列表