BCHE Overview
Molecule Name
Butyrylcholinesterase
Synonyms
Acylcholine acylhydrolase,BCHE,Butyrylcholine esterase,Butyrylcholinesterase,CHE1,CHE1cholinesterase,Choline esterase II,cholinesterase 1,E1,EC 3.1.1.8,Pseudocholinesterase
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs2
Highest Development StageApproved
Target Synonym
BCHED，CHE2，E1，Butyrylcholinesterase，BuChE，EC:3.1.1.8，EC 3.1.1，BCHE，Acylcholine acylhydrolase，Pseudocholinesterase，Cholinesterase，CHE1，Cholinesterase (Serum) 2，Butyrylcholine Esterase，Choline Esterase II，Cholinesterase 1，EC 3.1.1.8
Background
belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily.
BCHE Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Bisnorcymserine | ANVS-301 | Phase 1 Clinical | Horizon Therapeutics PLC, National Institute On Aging (NIA) | Alzheimer Disease | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Rivastigmine Tartrate | SDZ-212-713; SDZ 212713; SDZ-ENA-713; ONO-2540; ENA-713; ENA-713D | Approved | Novartis Pharma Ag | Exelon TDS, Rivastach, Exelon MR, Prometax, Exelon, 艾斯能 | EU | Alzheimer Disease; Parkinson Disease; Dementia | Novartis Europharm Ltd | 1998-05-11 | Alzheimer Disease; Anticholinergic Syndrome; Brain Injuries, Traumatic; Cocaine-Related Disorders; Cognition Disorders; Delirium; Dementia; Dementia, Vascular; Down Syndrome; Neurobehavioral Manifestations; Parkinson Disease; Substance-Related Disorders | Details |
| Rivastigmine Twice Weekly Transdermal Patch (Luye Pharma) | LY-03013; LY-30410; RID-TDS | Approved | Acino International AG | Rivirec, 金斯明, Kingsmin, Rivalif® | Mainland China | Alzheimer Disease | Luye Pharma Group Ltd | Alzheimer Disease; Parkinson Disease | Details |