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Axl

Axl信息

英文名称:AXL receptor tyrosine kinase上市药物数量2
中文名称AXL受体酪氨酸激酶临床药物数量30
靶点别称EC:2.7.10.1,EC 2.7.10,UFO,AXL Transforming Sequence/Gene,AXL Oncogene,EC 2.7.10.1,JTK11,Tyro7,ARK,Tyrosine-protein kinase receptor UFO,AXL,AXL Receptor Tyrosine Kinase最高研发阶段批准上市
英文名称:AXL receptor tyrosine kinase
中文名称AXL受体酪氨酸激酶
靶点别称EC:2.7.10.1,EC 2.7.10,UFO,AXL Transforming Sequence/Gene,AXL Oncogene,EC 2.7.10.1,JTK11,Tyro7,ARK,Tyrosine-protein kinase receptor UFO,AXL,AXL Receptor Tyrosine Kinase
上市药物数量2
临床药物数量30
最高研发阶段Approved

Axl产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (5)

  • 物种

    Human (3)Cynomolgus (1)

  • 标签

    His Tag (2)Fc Tag (1)Fc Tag & Avi Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (1)

共 4 项数据
  • 1

Axl分子背景

AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.

Axl分子别名

AXL,UFO

Licensing 项目合作

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