4-1BB Ligand 詳細
Molecule Name
Tumor necrosis factor ligand superfamily member 9
分子の別称
4-1BB Ligand,TNFSF9,CD137L
Drug Development Progress
治験薬の数2
市販薬剤の数0
研究＆開発段階Phase 2 Clinical
ターゲットの別称
4-1BB ligand，4-1BBL
バックグランド
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
4-1BB Ligand 製品リスト
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P***l2025-05-30Hi, I work for a start-up company, Nkure Therapeutics, in Bangalore. We have used GMP-4-1BBL from AcroBio and it worked well in our hands for a therapeutic dose. We culture primary cells as such NK cells to provide a cell therapy against cancer. We are happy with the service and the product quality as well. We compared the data of NK cell expansion with Croyez 4-1-BBL and AcroBio 4-1-BBL and realized there is no difference in the potency, however there is a huge difference in the price. AcroBio provides smaller pack size with a good price range as well.- a***n2025-02-06Your FACS antibodies of great. worked greatly to study immune cell and activation markers study with extradentary available conjugates for Flow cytometry