我的购物车

Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag

用户评价
货号-规格
价格
Qty.
合计0件 产品金额0
0
加入购物车

产品详情

  • 分子别名(Synonym)

    Neuraminidase/NA (Influenza Virus)

  • 表达区间及表达系统(Source)

    Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag (NEE-V524p) is expressed from human 293 cells (HEK293). It contains AA Val 80- Asn 469 (Accession # EPI2756234, GISAID).

    Predicted N-terminus: His

    Request for sequence

  • 蛋白结构(Molecular Characterization)

    Neuraminidase/NA (Influenza Virus) Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 44.9 kDa. The protein migrates as 52-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 偶联(Conjugate)

    Unconjugated

  • 内毒素(Endotoxin)

    Less than 1.0 EU per μg by the LAL method.

  • 纯度(Purity)

    90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

产品展示

  • 电泳(SDS-PAGE)

    Neuraminidase/NA (Influenza Virus) SDS-PAGE

    Influenza A (A/Georgia/12/2022 CVR-167) NA (A/pdm09 linage) Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • 活性(Bioactivity)-ELISA

     Neuraminidase/NA (Influenza Virus) ELISA

    Immobilized Influenza A (A/Georgia/12/2022 CVR-167) Neuraminidase (NA) (A/pdm09 linage) Protein, His Tag (Cat. No. NEE-V524p) at 1 μg/mL (100 μL/well) can bind Anti-NA(A/PAN) Antibody,Mouse IgG with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

用户评价
发表评论

背景介绍

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

前沿进展

 
联系我们
项目合作
查看更多项目
  • 产品SKU
  • 产品详情
  • 产品展示
  • 用户评价
  • 背景介绍