我的购物车

Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) (MALS verified)

用户评价
货号-规格
价格
Qty.
合计0件 产品金额0
0
加入购物车

产品详情

  • 抗体来源(Source)

    Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) is a Rabbit monoclonal antibody recombinantly expressed from HEK293 cells.

  • 克隆号(Clone)

    M1E04

  • 种属(Species)

    Rabbit

  • 亚型(Isotype)

    Rabbit IgG | Rabbit Kappa

  • 偶联(Conjugate)

    Unconjugated

  • 抗体类型(Antibody Type)

    Recombinant Monoclonal

  • 免疫原(Immunogen)

    MMAF-BSA.

  • 特异性(Specificity)

    Specifically recognizes MMAF, no recrecognizes MMAE.

  • 应用(Application)

    Application
    Recommended Usage
    ELISA
    0.06-125 ng/mL
  • 纯度(Purity)

    0.95 as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 纯化(Purification)

    Protein A purified / Protein G purified

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 交叉验证(Cross Verification)

    This product can cross in Elisa with

    MMAF.

    This product No cross-reactivity in ELISA with

    Doxorubicin.

    (PBD)SG3199.

    Monomethyl auristatin E.

    Trastuzumab Biosimilar.

  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

产品展示

  • 电泳(SDS-PAGE)

    MMAF SDS-PAGE

    Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 0.95 (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    MMAF SEC-MALS

    The purity of Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) (Cat. No. MMF-MY2219) is more than 90% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • 活性(Bioactivity)-ELISA

     MMAF ELISA

    Immobilized IgG1-MMAF at 0.1 μg/mL (100 μL/well) can bind Monoclonal Anti-MMAF specific Antibody, Rabbit IgG (M1E04) (Cat. No. MMF-MY2219) with a linear range of 0.06-8 ng/mL (QC tested).

    Protocol

用户评价
发表评论

背景介绍

Monomethyl auristatin F (MMAF) is a potent mitotic inhibitor that inhibits tubulin polymerization. MMAF is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several cancer types. Anti-MMAF antibody is a rabbit monoclonal antibody specifically reacts with MMAF without MMAE, which is more sensitive than mouse antibody. The anti-MMAF antibody is a useful reagent in PK assay to determine conjugated antibodies.

前沿进展

 
联系我们
项目合作
查看更多项目
  • 产品SKU
  • 产品详情
  • 产品展示
  • 用户评价
  • 背景介绍