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TGF-beta RII

TGF-beta RII信息

英文名称:Transforming growth factor beta receptor 2上市药物数量0
中文名称转化生长因子β受体2临床药物数量5
靶点别称NONHSAG034676，TGF-beta receptor type II，Transforming Growth Factor Beta Receptor 2，Transforming Growth Factor， Beta Receptor II Alpha，Transforming Growth Factor Beta Receptor Type IIC，Transforming growth factor-beta receptor type II，TbetaR-II，TGF-beta type II receptor，TGFBR2，Transforming Growth Factor， Beta Receptor II (70/80kDa)，Transforming Growth Factor Beta Receptor II，TGFR-2，Transforming Growth Factor， Beta Receptor II Epsilon，Transforming Growth Factor， Beta Receptor II Delta，Transforming Growth Factor， Beta Receptor II Gamma，EC 2.7.11，Transforming Growth Factor， Beta Receptor II Beta，TGF-Beta Receptor Type IIB，TGF-Beta Receptor Type-2，EC 2.7.11.30，TGFbeta-RII，TBR-Ii，LDS1B，LDS2B，TAAD2，TBRII，AAT3，FAA3，LDS2，RIIC，MFS2，Receptor， Transforming Growth Factor-beta Type II，EC:2.7.11.30最高研发阶段Phase 2 Clinical
英文名称:Transforming growth factor beta receptor 2
中文名称转化生长因子β受体2
靶点别称NONHSAG034676，TGF-beta receptor type II，Transforming Growth Factor Beta Receptor 2，Transforming Growth Factor， Beta Receptor II Alpha，Transforming Growth Factor Beta Receptor Type IIC，Transforming growth factor-beta receptor type II，TbetaR-II，TGF-beta type II receptor，TGFBR2，Transforming Growth Factor， Beta Receptor II (70/80kDa)，Transforming Growth Factor Beta Receptor II，TGFR-2，Transforming Growth Factor， Beta Receptor II Epsilon，Transforming Growth Factor， Beta Receptor II Delta，Transforming Growth Factor， Beta Receptor II Gamma，EC 2.7.11，Transforming Growth Factor， Beta Receptor II Beta，TGF-Beta Receptor Type IIB，TGF-Beta Receptor Type-2，EC 2.7.11.30，TGFbeta-RII，TBR-Ii，LDS1B，LDS2B，TAAD2，TBRII，AAT3，FAA3，LDS2，RIIC，MFS2，Receptor， Transforming Growth Factor-beta Type II，EC:2.7.11.30
上市药物数量0
临床药物数量5
最高研发阶段Phase 2 Clinical

TGF-beta RII产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (6)

  • 物种

    Human (5)Mouse (1)

  • 标签

    Fc Tag (1)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)His Tag (1)Llama IgG Fc Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (3)

共 6 项数据
  • 1

TGF-beta RII分子背景

TGF-beta receptor type-2 (TGFBR2 or TGFR-2) is also known as TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TbetaR-II, TGFβR2, which is a homodimer or heterohexamer, belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family and TGFB receptor subfamily. TGFR2 / TGFBR2 binds TGF-β1 / TGFB1 and TGF-β3 / TGFB3 with high affinity and TGF-β2 / TGFB2 with a much lower affinity. This type I I receptor forms a heterodimeric complex with type I receptor and is essential for signal transduction. Upon ligand binding, the TGFR2 autophosphorylates its cytoplasmic domain and subsequently phosphorylates the downstream molecules which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

TGF-beta RII分子别名

TGFBR2,TGFR2,TbetaR-II,TGFβR2

产品评论

  • 2022-08-17
    1人点赞
    Human TGF-beta RII / TGFBR2 Protein, His Tag (MALS verified)
    I ordered Acro’s human TGF-beta Receptor II for Octet kinetics binding assays for several assays. Delivery was extremely quick and customer service was very responsive to questions I had. I first used this TGF-beta RII in an Octet binding kinetics assay and received high quality results that were consistent with what I expected. I also used this product as a TGF-beta sink in cytotoxicity assays. I have been impressed by the quality of Acro’s products.
  • In****** 2021-10-22
    0人点赞
    Human TGF-beta RII / TGFBR2 Protein, His Tag (MALS verified)
    用过很多次acro家的产品，这个蛋白用于细胞功能实验，活性好，实验内表现出非常好的活性和灵敏度。
  • 分子信息
  • 产品列表