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LRP-6

LRP-6信息

英文名称:Low-density lipoprotein receptor-related protein 6上市药物数量0
中文名称低密度脂蛋白受体相关蛋白6临床药物数量0
靶点别称LDL Receptor Related Protein 6，LRP6最高研发阶段Preclinical
英文名称:Low-density lipoprotein receptor-related protein 6
中文名称低密度脂蛋白受体相关蛋白6
靶点别称LDL Receptor Related Protein 6，LRP6
上市药物数量0
临床药物数量0
最高研发阶段Preclinical

LRP-6产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    Mouse IgG Fc Tag (1)His Tag & Avi Tag (1)

  • 标记

    Unconjugated (1)Biotin-labeled (1)

共 2 项数据
  • 1

LRP-6分子背景

LRP6 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP5. Low-density lipoprotein receptor-related protein 6 is a key component of the LRP5/LRP6/Frizzled co-receptor group that is involved in canonical Wnt pathway. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.

LRP-6分子别名

LRP-6,LRP6
  • 分子信息
  • 产品列表